Immune function in marathon runners

摘要: Quantitative immunoglobulins (IgG, IgA, IgM) and leukocyte phagocytosis killing were studied in 20 male marathon runners to determine if rigorous physical conditioning affects immune function. C3, C4, Properdin Factor B, T B cells, phytohemagglutinin pokeweed mitogen stimulation of lymphocytes determined selected runners. Complete blood counts, including platelets, obtained for the group. Mean immunoglobulin values IgG, IgA IgM within normal limits. Ten (50%) had slightly low total lymphocyte counts (less than 1500/mm3). Leukocyte was consistently normal. Nine marathoners felt that running increased, one it decreased their resistance respiratory infections. This could not, however, be correlated with significant changes parameters. We conclude long distance has no effect on