A meta-analysis of studies of dietary fat and breast cancer risk

摘要: There is strong evidence that breast cancer risk influenced by environmental factors, and animal experiments human ecological data suggest increased dietary fat intake increases the incidence of disease. Epidemiological on relationship to from cohort case control studies has however been inconsistent. To examine available we have carried out a meta-analysis summarise quantitatively large published literature in aetiology cancer. After assembling all studies, extracted relative each study compared highest lowest level intake. We then calculated summary for studies. The 23 examined as nutrient was 1.12 (95% CI 1.04-1.21). Cohort had 1.01 0.90-1.13) 1.21 1.10-1.34). Summary estimates specific types excluded unity only saturated fat. For 19 food intake, risks were 1.18 1.06-1.32) meat, 1.17 1.04-1.31) milk, 1.02-1.36) cheese. total several potential modifying factors. Regression analysis showed European more likely than done other countries show an associated with cancer, after taking into account factors included design quality.