The endocrine regulation of exocrine pancreas in preruminant milk-fed calves.

作者: J. Lefaivre , J. P. Barlet , M. J. Davicco

DOI:

关键词:

摘要: Fifteen male Holstein X Frisian calves, weighing 65 +/- 3 kg and fed a milk replacer twice daily were fitted with return cannula loop, chronically implanted at 10 days of age in the pancreatic duct, used. In six successive experiments we have observed influence an intravenous infusion secretin, cholecystokinin pancreozymin (CCK-PZ), vasoactive intestinal peptide (VIP), glucagon, gastrin somatostatin on juice flow rate, excretion proteins, calcium, inorganic phosphorus, zinc amylase activity juice. two other experiments, studied interaction secretin (or CCK-PZ) (SRIF). Each experiment was performed 5 h after calves feeding no given to animals during time sampling. Our results indicate that endocrine regulation exocrine pancreas young is similar described mammals. Secretin CCK-PZ increased significantly water, magnesium, zinc, proteins activity. Somatostatin glucagon inhibited effects precedent hormones. Gastrin rate but protein do not varied significantly. VIP showed significant effect minerals, However, our seem be characterized by more intense following than infusion.

参考文章(9)
W.J. Rutten, J.J.H.H.M. de Pont, S.L. Bonting, Adenylate cyclase in the rat pancreas properties and stimulation by hormones Biochimica et Biophysica Acta (BBA) - Biomembranes. ,vol. 274, pp. 201- 213 ,(1972) , 10.1016/0005-2736(72)90294-5
V. Wizemann, P. Weppler, R. Mahrt, Effect of glucagon and insulin on the isolated exocrine pancreas. Digestion. ,vol. 11, pp. 432- 435 ,(1974) , 10.1159/000197612
MICHAEL SHEPPARD, BRAHM SHAPIRO, BERNARD PIMSTONE, SHIRLEY KRONHEIM, MICHAEL BERELOWITZ, MARTIN GREGORY, Metabolic Clearance and Plasma Half-Disappearance Time of Exogenous Somatostatin in Man The Journal of Clinical Endocrinology and Metabolism. ,vol. 48, pp. 50- 53 ,(1979) , 10.1210/JCEM-48-1-50
K. G. Wormsley, The action of secretin on the secretion of enzymes by the human pancreas. Scandinavian Journal of Gastroenterology. ,vol. 3, pp. 183- 188 ,(1968) , 10.3109/00365526809180120
Ch. Steffen, H. Goebell, G. Baltzer, H. K. Dürr, Untersuchungen zum Hemmeffekt von Glucagon auf die Pankreassekretion des Menschen J.F. Bergmann-Verlag, Munich. pp. 1423- 1425 ,(1972) , 10.1007/978-3-642-85448-4_356
T. Scratcherd, R. M. Case, The secretion of electrolytes by the pancreas. The American Journal of Clinical Nutrition. ,vol. 26, pp. 326- 339 ,(1973) , 10.1093/AJCN/26.3.326
GF Stening, MI Grossman, Gastrin-related peptides as stimulants of pancreatic and gastric secretion. American Journal of Physiology. ,vol. 217, pp. 262- 266 ,(1969) , 10.1152/AJPLEGACY.1969.217.1.262