Coronary artery disease in systemic lupus erythematosus: risk factors, assessment, and prevention.

摘要: The 10-year survival rate of patients with systemic lupus erythematosus (SLE) currently is more than 85|X%; the greater longevity permits late complications to emerge. Recent studies have shown an increased incidence coronary artery disease (CAD), frequently in young adults. CAD among most common causes death SLE who survive longer 5 years. Multiple risk factors, some specific SLE, are implicated premature development CAD. These include vasculitis, hypertension and hyperlipidemia, corticosteroid therapy, antiphospholipid antibodies, which may result thrombotic events. Therefore, factors for should be actively sought as part routine care appropriate modification strategies, including medications if necessary, employed. Noninvasive cardiac tests used early evaluation any symptoms consistent myocardial ischemia, heart failure, or arrhythmias.