Red cell aplasia and osteoblastic metastases in a patient with thymoma

摘要: A case is reported of transient red cell aplasia in a patient with metastatic thymoma. 32-year-old Caucasian man who was treated x-ray therapy to the thymus childhood had thymoma removed at age 28. Two years later, nodules were found lungs. He started on monthly injections nitrogen mustard. Eleven months and one month after his last dose mustard, he developed severe anemia associated absent precursors marrow. Concomitantly, discovered have scattered osteoblastic bone lesions proven by biopsy be secondary uiymoma. The additional findings lymphopenia, anergy, basal carcinoma skin support contention that impairment thymus-dependent immune system present.