Environmental fate of bisphenol A and its biological metabolites in river water and their xeno-estrogenic activity.

摘要: Monitoring of bisphenol A [BPA; 2,2-bis(4-hydroxyphen- yl)propane] and its biological metabolites [4,4‘-dihydroxy-α-methylstilbene (DHMS), 2,2-bis(4-hydroxyphenyl)-1-propanol (BPA-OH), 2,2-bis(4-hydroxyphenyl)propanoic acid (BPA-COOH), 2-(3,4-dihydroxyphenyl)-2-(4-hydroxyphenyl)propane (3-OH-BPA)] in river waters was performed by solid-phase extraction GC/MS de termination. The concentrations BPA, BPA-COOH, BPA-OH, 3-OH-BPA the water ranged from 2 to 230 (8.8 × 10-12 1.0 10-9 M), 5 75 (1.9 10-11 2.9 10-10 3 16 (1.2 6.6 11 4.5 M) ng L-1, respectively. DHMS, an intermediate main degradation pathway not detected any sample. Under aerobic conditions water, BPA disappeared within 8 d incubation, but tetraol remained supernatant after 14 incubation. For xeno-estrogenic activity metabolites, their ...