Decarboxylation of 2-keto fatty acids by brain

作者: W. Ewart Davies , Amiya K. Hajra , Surendra S. Parmar , Norman S. Radin , James F. Mead

DOI: 10.1016/S0022-2275(20)39292-0

关键词:

摘要: An enzyme system consisting of washed acetone powder pig brain, adenosine triphosphate, nicotinamide adenine dinucleotide, magnesium, fumaric acid, and ascorbic acid was found to catalyze the oxidative decarboxylation 2-ketostearic acid. The products were carbon dioxide heptadecanoic Washing with ethylene-diaminetetraacetate other chelating agents destroyed activity. Further properties are described. It is believed that this accounts in part for 1-carbon degradation route brain fatty acids.

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