Method of enhancing NMR imaging using chelated paramagnetic ions bound to biomolecules

作者: Ulrich Speck , Hanns-Joachim Weinmann , Heinz Gries , Georg-Alexander Hoyer , Heinrich Pfeiffer

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摘要: Agents useful for influencing the relaxation times in NMR diagnostics, contain at least one paramagnetic, physiologically compatible complex salt comprising a chelate from an open-chain or cyclic complex-forming compound containing organic nitrogen, phosphorus, oxygen and/or sulfur, and complexed ion of lanthanide elements atomic number 57-70 transition metals numbers 21-29, 42 44, and, optionally, inorganic base acid, wherein said is bound to biomolecule.

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