Benzothiazole and thiazole[5,5-b] pyridine compositions and their use as ubiquitin ligase inhibitors
作者： Usha V. Ramesh , Raymond Lowe , Donald G. Payan , Francesco Parlati , Rajinder Singh
DOI:
关键词:
摘要: This invention describes compounds and pharmaceutical compositions useful as ubiquitin agent inhibitors. The of the are inhibitors biochemical pathways organisms in which ubiquitination is involved. also comprises use for treatment conditions that require inhibition ubiquitination. Furthermore, methods inhibiting a cell comprising contacting desired with composition according to invention.
lens.org 参考文章(6)
Barbara Scott, Kevin P. Cusack, Lee D. Arnold, Anna Ericsson, 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors ,(2001)
Alexis Borisy, Brent R. Stockwell, Michael A. Foley, Curtis Keith, Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders ,(2002)
Kazuyoshi Raitobiru Miyata, Yoshihiko Aza Maehama Tsuda, Yasuo Shinseibiru Shoji, Chieko Aza Ebisu Maehigashi Naba, Kazuhiko Tenjin Tsutsumi, Yasuhisa Vilasezon Aza Gomai Kurogi, Yasuhide Aza Sannokoshi Inoue, Phosphonic diester derivative ,(1994)
Charles O. Okafor, Heterocyclic series. II. 3,6-Diazaphenothiazine sulfoxides and other potential antiparasitic and pesticidal agents Journal of Chemical & Engineering Data. ,vol. 16, pp. 244- 246 ,(1971) , 10.1021/JE60049A037
Yasufumi Nagata, Teruyuki Nishimura, Tomoharu Iino, Junichi Eiki, Novel aminobenzamide derivative ,(2003)
Christer Sahlberg, Hans Wallberg, Lotta Naeslund, Genaidy Kalyanov, Lourdes Salvador Odén, Stefan Lindström, Non-nucleoside reverse transcriptase inhibitors ,(2011)