Preparation of pH-adjusted local anesthetics.

摘要: Characteristics of alkalinized local anesthetics are poorly described with regard to stability and precipitation. Current fixed-volume methods alkalinization often result in unstable, precipitated solutions unpredictable pH. We determined a stable, nonprecipitating, anesthetic mixture used it randomized double-blind crossover study 21 patients evaluate reducing pain on injection. Our solution significantly reduced associated retrobulbar injection (analysis variance, P = .0362) but not that Nadbath Fixed-volume is recommended because complications can the use anesthetics.