Compositions and methods for therapy and diagnosis of breast cancer
作者： Craig H. Day , Davin C. Dillon , Yuqiu Jiang , Raymond L. Houghton , Aijun Wang
DOI:
关键词:
摘要: Compositions and methods for the therapy diagnosis of cancer, such as breast are disclosed. may comprise one or more tumor proteins, immunogenic portions thereof, polynucleotides that encode portions. Alternatively, a therapeutic composition an antigen presenting cell expresses protein, T is specific cells expressing protein. Such compositions be used, example, prevention treatment diseases cancer. Diagnostic based on detecting mRNA encoding in sample also provided.
lens.org 参考文章(249)
Manuela Haltmeier, Wolfgang Seifarth, Jürgen Blusch, Volker Erfle, Rüdiger Hehlmann, Christine Leib-Mösch, Identification of S71-related human endogenous retroviral sequences with full-length pol genes. Virology. ,vol. 209, pp. 550- 560 ,(1995) , 10.1006/VIRO.1995.1287
Rakesh K. Jain, Barriers to drug delivery in solid tumors. Scientific American. ,vol. 271, pp. 58- 65 ,(1994) , 10.1038/SCIENTIFICAMERICAN0794-58
S. W. Lee, C. Tomasetto, R. Sager, Positive selection of candidate tumor-suppressor genes by subtractive hybridization. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 2825- 2829 ,(1991) , 10.1073/PNAS.88.7.2825
Thomas Werner, Ruth Brack-Werner, Christine Leib-Mösch, Horst Backhaus, Volker Erfle, Rüdiger Hehlmann, S71 is a phylogenetically distinct human endogenous retroviral element with structural and sequence homology to simian sarcoma virus (SSV) Virology. ,vol. 174, pp. 225- 238 ,(1990) , 10.1016/0042-6822(90)90071-X
Michael Mitas, Kaidi Mikhitarian, Christian Walters, Paul L. Baron, Bruce M. Elliott, Thomas E. Brothers, Jay G. Robison, John S. Metcalf, Yuko Y. Palesch, Zhen Zhang, William E. Gillanders, David J. Cole, Quantitative real-time RT-PCR detection of breast cancer micrometastasis using a multigene marker panel. International Journal of Cancer. ,vol. 93, pp. 162- 171 ,(2001) , 10.1002/IJC.1312
Douglas J. Schwartzentruber, Suzanne L. Topalian, Steven A. Rosenberg, Gang Zeng, Samuel L. Johnston, Rong Fu Wang, A Breast and Melanoma-Shared Tumor Antigen: T Cell Responses to Antigenic Peptides Translated from Different Open Reading Frames Journal of Immunology. ,vol. 161, pp. 3596- 3606 ,(1998)
Nancy M. Lee, Horace H. Loh, Therapeutic uses of dynorphin ,(1981)
Jeffrey Skolnick, Jacquelyn S. Fetrow, From genes to protein structure and function: novel applications of computational approaches in the genomic era Trends in Biotechnology. ,vol. 18, pp. 34- 39 ,(2000) , 10.1016/S0167-7799(99)01398-0
M Bernard, H Yoshioka, E Rodriguez, M Van der Rest, T Kimura, Y Ninomiya, B R Olsen, F Ramirez, Cloning and sequencing of pro-alpha 1 (XI) collagen cDNA demonstrates that type XI belongs to the fibrillar class of collagens and reveals that the expression of the gene is not restricted to cartilagenous tissue. Journal of Biological Chemistry. ,vol. 263, pp. 17159- 17166 ,(1988) , 10.1016/S0021-9258(18)37512-4
ALEXEI F. KIRKIN, KARINE DZHANDZHUGAZYAN, JESPER ZEUTHEN, Melanoma-associated antigens recognized by cytotoxic T lymphocytes Apmis. ,vol. 106, pp. 665- 679 ,(1998) , 10.1111/J.1699-0463.1998.TB00210.X