Beyond Skin Tumors: A Systematic Review of Mohs Micrographic Surgery in the Treatment of Deep Cutaneous Fungal Infections.

作者: Hanieh Zargham , Sofianne Gabrielli , Cerrene N. Giordano , Harold William Higgins

DOI: 10.1097/DSS.0000000000002761

关键词:

摘要: Background Deep cutaneous fungal infections (DCFIs) can cause significant morbidity in immunocompromised patients and often fail medical standard surgical treatments because of subclinical extension. Although rarely considered this setting, Mohs micrographic surgery (MMS) offers the advantages comprehensive margin control tissue conservation, which may be beneficial treatment DCFIs that have failed options. Objective To review benefits, limitations, practicality MMS with DCFIs. Methods A systematic PubMed EMBASE was conducted to identify all cases skin lesions treated MMS. Results Eight case reports were identified consisting a total 8 patients. majority had predisposing comorbidity (75%), most common being solid organ transplant (n = 3, 37.5%). The commonly diagnosed infection phaeohyphomycosis 5, 62.5%), followed by mucormycosis 2, 25%). No recurrence or complication post-MMS noted at mean follow-up 11.66 months. Conclusion not first-line treatment, as an effective alternative for failure particularly helpful areas where conservation is imperative.

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