Chapter 14 Erythrocyte sugar transport

作者: A. Carruthers , R.J. Zottola

DOI: 10.1016/S1383-8121(96)80055-8

关键词:

摘要: Publisher Summary The net sugar transport by human erythrocytes is the sum of two sequential processes—sugar translocation and reversible intracellular binding. Sugar binding may occur either at endofacial GLUT1 sites or a complex in very close association with glucose transporter. Therefore, steady-state measurements that report both steps cannot be used directly for modeling process isolation. This also illustrates potential control recruitment complexes to transporter—a thymocytes, CHO cells macrophages. interpretation steady state data must carried out cautiously. It remains formally possible can modeled successfully one more hypothetical mechanisms. Exchange data, inhibition ligand results suggest system does not function as simple carrier but rather, bind export import ligands simultaneously.

参考文章(107)
M.A. Zoccoli, S.A. Baldwin, G.E. Lienhard, The monosaccharide transport system of the human erythrocyte. Solubilization and characterization on the basis of cytochalasin B binding. Journal of Biological Chemistry. ,vol. 253, pp. 6923- 6930 ,(1978) , 10.1016/S0021-9258(17)38008-0
Virgilio L. Lew, J. C. Ellory, Membrane transport in red cells. Academic Press.. ,(1977)
Wilfred D. Stein, W. R. Lieb, Transport and Diffusion Across Cell Membranes ,(1986)
J. D. Young, J. Clive Ellory, Red cell membranes, a methodological approach Academic Press. ,(1982)
Narla Mohandas, Stephen B. Shohet, Red Cell Membranes ,(1988)
A.L. Helgerson, A. Carruthers, Equilibrium ligand binding to the human erythrocyte sugar transporter. Evidence for two sugar-binding sites per carrier. Journal of Biological Chemistry. ,vol. 262, pp. 5464- 5475 ,(1987) , 10.1016/S0021-9258(18)45595-0
J. Cuppoletti, C.Y. Jung, F.A. Green, Glucose transport carrier of human erythrocytes. Radiation target size measurement based on flux inactivation. Journal of Biological Chemistry. ,vol. 256, pp. 1305- 1306 ,(1981) , 10.1016/S0021-9258(19)69964-3
D.M. Miller, The Kinetics of Selective Biological Transport Biophysical Journal. ,vol. 8, pp. 1339- 1352 ,(1968) , 10.1016/S0006-3495(68)86560-9