摘要: Objective : Substantial progress has been made in identifying how the treatment parameters used ECT impact on cognitive side effects. However, there is limited information regarding individual differences vulnerability to these The authors examined patients' pretreatment global status and postictal orientation recovery time as potential predictors of magnitude retrograde amnesia for autobiographical memories after ECT. Method Seventy-one inpatients with major depressive disorder were randomly assigned four conditions that varied electrode placement (right unilateral versus bilateral) stimulus dosage (low high intensity). Orientation was assessed at virtually every session during course Global modified Mini-Mental State examination before treatment, week termination 2 months ended. Retrograde same points Autobiographical Memory Interview. Results Pre-ECT duration disorientation strong 2-month follow-up. In general, relationships maintained regardless technical administration Conclusions Patients who manifest impairment patients experience prolonged acute period may be most vulnerable persistent information.