摘要: The genus Mycobacterium includes some of the most common causes human morbidity and mortality worldwide. tuberculosis is a commonly cited example, resulting in almost 10 million new cases 1.5 deaths each year, although regions, nontuberculous mycobacteria (NTM) probably cause more disease. Mycobacteria represent challenging pathogens, as they are intrinsically resistant to many used antimicrobials. Therefore, with acquisition mutations conferring additional resistance phenotypes, these pathogens can readily lead disease essentially no effective chemotherapeutic options. This review provides brief overview broad spectrum mycobacterial antimicrobials limitations it places on therapeutic
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