Contemporary Research in Behavioral Pharmacology

摘要: 1 * Schedule-Controlled Behavior and the Effects of Drugs.- 1. Introduction.- 2. Behavior.- 2.1. Processes Reinforcement Punishment.- 2.2. Schedules Other Determinants 2.3. Control by Noxious Stimuli.- 2.4. Nature Significance 3. Drugs on 3.1. Response Rate as a Determinant Behavioral 3.2. Behaviors Maintained Different Events.- 3.3. Punished Responding.- 4. Summary Conclusions.- 5. References.- 2 The Controlled Aversive Stimul.- 1.1. Methodological Issues Surrounding Use Electric Shock.- 1.2. Problems Associated with Operant That Utilize Drug-Behavior Interactions in Conflict-Punishment Procedures.- Geller Conflict Schedule.- Punishment Species.- Review Drug upon Standard Paradigm.- Analysis Mechanisms Which May Affect 2.5. Alter Synaptic Activity 2.6. Summary.- Continuous Avoidance Terms Motivational Processes.- Literature.- 3.4. Classification Bovet-Gatti Profiles.- 3.5. 3.6. Conclusions Concerning Conditioned Emotional Response.- 4.1. CER Technique.- 4.2. CER.- 4.3. 4.4. General 6. 3 Stimulus Effects.- Multiple Related SD-S? Schedules.- SD-SDMultiple SD-SD Two-Key Chained Signaled Fixed Consecutive Number.- Matching to Sample.- Repeated Acquisition Chains.- 4 Drug-Induced Control.- Scope.- Terminology.- Methods for Demonstration Choice.- Emission.- Comment.- Interpretations Dimensions.- Data.- Origin Epilogue.- 5 Adjunctive Examples 1.3. Schedule-Induced 1.4. Importance Pharmacology.- Amphetamines.- Anxiolytics.- Anticholinergic Central 6 Self-Administration Ethanol Consumption.- Lester's Original Observations.- Differences between Polydipsia Water Polydipsia.- Schedule Induction Means Generating Excessive Ethanol's Calorific Value.- Pharmacological Effect.- Taste.- under Conditions Loss Inducing Consumption Than Ethanol.- An Animal Model Human Alcoholism.- 5.1. Forced 5.2. Intravenous Intragastric Self-Administration.- 5.3. 7. 7 Reinforcers.- Establishment Fixed-Ratio Fixed-Interval Complex Type Drug.- Magnitude Reinforcement.- Satiation Deprivation.- Negative 8. 9. Application Techniques: Preclinical Assessment Abuse Liability New Compounds.- 10. Studies.- 11. 12. 8 Tolerance.- Tolerance Perspective.- Metabolic Learned Acute Cross Sensitization (Reverse Tolerance).- Organismic Factors.- Dose Level.- Frequency.- Topography.- Environmental Factors: Density Hypothesis.- Data Consistent Direct Support from Differential Exceptions.- Properties 9 Toxicology.- What Is Toxicology?.- Origins Distinguishing Features Qualitative Evaluation Role Threshold Estimates.- Chronicity Factor.- Complications Chronic Multidisciplinary Features.- Toxicology Soviet Union.- Substances Current Interest.- Mercury.- Lead.- Carbon Monoxide.- Pesticides.- 4.5. Volatile Anesthetics Solvents.- Factors Modulate Toxins.- Diurnal Rhythms.- Degree Discriminative 5.4. Complexity.- Future Developments.- 6.1. Food Additives.- 6.2. Teratology.- 6.3. Evaluations Natural Environment.- 6.4. Premarket Screening.- Author Index.