Leisure-time physical activity and lung cancer: a meta-analysis

摘要: Objective: Several studies have evaluated the relationship between physical activity and lung cancer. To summarize review these studies, we conducted a meta-analysis of all relevant reports published from 1966 through October 2003. Method: Adjusted odds ratios (ORs) original were pooled by inverse their variance, estimates accompanied an assessment heterogeneity across investigations. Test for linear trend categories (low, moderate, high) applied. Results: The combined ORs 0.87 (95 confidence interval=0.79–0.95) moderate leisure-time (LPA) 0.70 (0.62–0.79) high (ptrend = 0.00). This association occurred both sexes, although it was somewhat stronger women. No evidence publication bias found. able to adjust smoking, but none adjusted possible confounding previous malignant respiratory disease. Our simulations suggest that this condition is unlikely entirely explain association. Conclusion: findings indicate higher levels LPA protect against remains confounded inadequately controlled smoking patterns. However on whole, seems explanation individual non-smokers.