Reactive oxygen species: the root cause of nanoparticle-induced toxicity in Drosophila melanogaster.

摘要: Nanotechnology is a rapidly developing technology in the twenty-first century. Nanomaterials are extensively used numerous industries including cosmetics, food, medicines, industries, agriculture, etc. Along with its wide application toxicity also reported from studies of various model organisms Drosophila. The reflects cytotoxicity, genotoxicity, and teratogenicity. current study correlates as consequence reactive oxygen species (ROS) generated owing to presence nanoparticles living cell. ROS mainly includes hydroxyl ions, peroxide superoxide anions, singlet oxygen, hypochlorous acids. An elevated level can damage cells by means. To protect body excess ROS, possess set antioxidant enzymes which peroxidase, glutathione catalase. If cannot nullify than DNA damage, cell apoptosis, uncontrolled regulations occur resulting abnormal physiological genotoxic conditions. Herewith, we reporting morphological defects caused after nanoparticle treatment function redox imbalance.