USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation

作者: Sabrina Torre , Maria J Polyak , David Langlais , Nassima Fodil , James M Kennedy

DOI: 10.1038/NI.3581

关键词:

摘要: … USP15 (Usp15 L749R ) that conveyed resistance to both ECM and EAE. We found that USP15-… The E3 ubiquitin ligase TRIM25 is a target of USP15 (refs. 22,23). Using biochemical, …

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