作者: Jan Tesařík , Milan Dvořak
DOI: 10.1016/S0022-5320(82)80013-0
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摘要: The preovulatory development of the human cumulus oophorus was studied using transmission and scanning electron microscopy histochemical freeze-fracture techniques. It divided into three phases. In phase I oocyte—cumulus cell gap junctions reveal changes typical for uncoupling; numerous desmosomes, small junctions, intermediate are present between closely contacting cells. II disappear as well desmosomes cells, now creating wide intercellular spaces. These spaces permeated by processes, connecting adjacent cells via various-sized junctions. Ultrastructurally bears signs early luteinization. Phase III is marked appearance matrix glycoprotein nature. Gap absent. This study has emphasized complicated interactions junction-utilizing system involving follicular fluid inhibitors in control follicle development.