SHP-1 and PDK1 Form a Phosphotyrosine-Dependent Nucleo-Cytoplasmic Shuttling Complex: Implications for Differentiation

Michael P. Scheid, Michael Parsons, James R. Woodgett, Phosphoinositide-Dependent Phosphorylation of PDK1 Regulates Nuclear Translocation Molecular and Cellular Biology. ,vol. 25, pp. 2347- 2363 ,(2005) , 10.1128/MCB.25.6.2347-2363.2005

Y Xu, D D Mousseau, D Banville, X Zhao, S-H Shen, SHP-1 sensitizes MCF-7 cells to trichostatin A-induced apoptosis by modulating PI3K-dependent events Cell Death & Differentiation. ,vol. 10, pp. 1213- 1214 ,(2003) , 10.1038/SJ.CDD.4401292

Daniel J. Freeman, Andrew G. Li, Gang Wei, Heng-Hong Li, Nathalie Kertesz, Ralf Lesche, Andrew D. Whale, Hilda Martinez-Diaz, Nora Rozengurt, Robert D. Cardiff, Xuan Liu, Hong Wu, PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms Cancer Cell. ,vol. 3, pp. 117- 130 ,(2003) , 10.1016/S1535-6108(03)00021-7

Haihua Gu, Hiroyuki Maeda, James J. Moon, James D. Lord, Monique Yoakim, Brad H. Nelson, Benjamin G. Neel, New Role for Shc in Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway Molecular and Cellular Biology. ,vol. 20, pp. 7109- 7120 ,(2000) , 10.1128/MCB.20.19.7109-7120.2000

Anne Brunet, Azad Bonni, Michael J Zigmond, Michael Z Lin, Peter Juo, Linda S Hu, Michael J Anderson, Karen C Arden, John Blenis, Michael E Greenberg, Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor Cell. ,vol. 96, pp. 857- 868 ,(1999) , 10.1016/S0092-8674(00)80595-4

Katherine A. Siminovitch, Katherine A. Siminovitch, Qin Dong, Gregory P. Downey, Lea Fialkow, Takeyasu Fukushima, Negative Regulation of Myeloid Cell Proliferation and Function by the SH2 Domain-Containing Tyrosine Phosphatase-1 Journal of Immunology. ,vol. 162, pp. 3220- 3230 ,(1999)

A. Takano, T. Haruta, M. Iwata, I. Usui, T. Uno, J. Kawahara, E. Ueno, T. Sasaoka, M. Kobayashi, Growth Hormone Induces Cellular Insulin Resistance by Uncoupling Phosphatidylinositol 3-Kinase and Its Downstream Signals in 3T3-L1 Adipocytes Diabetes. ,vol. 50, pp. 1891- 1900 ,(2001) , 10.2337/DIABETES.50.8.1891

James I. Healy, Christopher C. Goodnow, POSITIVE VERSUS NEGATIVE SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS Annual Review of Immunology. ,vol. 16, pp. 645- 670 ,(1998) , 10.1146/ANNUREV.IMMUNOL.16.1.645

Kohjiro Ueki, Petra Algenstaedt, Franck Mauvais-Jarvis, C. Ronald Kahn, Positive and Negative Regulation of Phosphoinositide 3-Kinase-Dependent Signaling Pathways by Three Different Gene Products of the p85α Regulatory Subunit Molecular and Cellular Biology. ,vol. 20, pp. 8035- 8046 ,(2000) , 10.1128/MCB.20.21.8035-8046.2000

Mathieu Bollen, Combinatorial control of protein phosphatase-1 Trends in Biochemical Sciences. ,vol. 26, pp. 426- 431 ,(2001) , 10.1016/S0968-0004(01)01836-9