摘要: Restless legs syndrome is a common condition characterized by unpleasant limb sensations that are precipitated rest and relieved activity. Symptoms worse during the evening may result in insomnia. Most cases idiopathic, although sometimes familial be associated with range of medical illnesses, including chronic renal failure iron deficiency anemia. responsive to several medications, levodopa, dopamine agonists, benzodiazepines, opioids, some anticonvulsants. A practical approach management involves stepwise plan, commencing intermittent therapy less potent agents for mild progressing medications greater potency but higher potential side effects.
mayoclinicproceedings.org
sci-hub.se 参考文章(13)
Richard P. Allen, Christopher J. Earley, Augmentation of the restless legs syndrome with carbidopa/levodopa. Sleep. ,vol. 19, pp. 205- 213 ,(1996) , 10.1093/SLEEP/19.3.205
A clinical and polysomnographic comparison of neuroleptic-induced akathisia and the idiopathic restless legs syndrome. Sleep. ,vol. 14, pp. 339- 345 ,(1991) , 10.1093/SLEEP/14.4.339
J. Montplaisir, O. Lapierre, H. Wames, G. Pelletier, The treatment of the restless leg syndrome with or without periodic leg movements in sleep. Sleep. ,vol. 15, pp. 391- 395 ,(1992) , 10.1093/SLEEP/15.5.391
Randomized, double-blind, placebo-controlled study of clonidine in restless legs syndrome. Sleep. ,vol. 19, pp. 52- 58 ,(1996) , 10.1093/SLEEP/19.1.52
Arthur S. Walters, Mary L. Wagner, Wayne A. Hening, Kenneth Grasing, Richard Mills, Sudhansu Chokroverty, Neil Kavey, Successful treatment of the idiopathic restless legs syndrome in a randomized double-blind trial of oxycodone versus placebo. Sleep. ,vol. 16, pp. 327- 332 ,(1993) , 10.1093/SLEEP/16.4.327
Sonia Ancoli-Israel, Sonia Ancoli-Israel, tDaniel F. Kripke, tDaniel F. Kripke, Melville R. Klauber, William J. Mason, William J. Mason, Robert Fell, Robert Fell, Oscar Kaplan, Periodic limb movements in sleep in community-dwelling elderly. Sleep. ,vol. 14, pp. 496- 500 ,(1991) , 10.1093/SLEEP/14.6.496
A. S. Walters, K. Hickey, J. Maltzman, T. Verrico, D. Joseph, W. Hening, V. Wilson, S. Chokroverty, A questionnaire study of 138 patients with restless legs syndrome: the 'Night-Walkers' survey. Neurology. ,vol. 46, pp. 92- 95 ,(1996) , 10.1212/WNL.46.1.92
Arthur S. Walters, Michael S. Aldrich, Richard Allen, Sonia Ancoli-Israel, David Buchholz, Sudhansu Chokroverty, Giorgio Coccagna, Christopher Earley, Bruce Ehrenberg, T. G. Feest, Wayne Hening, Neil Kavey, Gilles Lavigne, Joseph Lipinski, Elio Lugaresi, Pasquale Montagna, Jacques Montplaisir, Sarah S. Mosko, Wolfgang Oertel, Daniel Picchietti, Thomas Pollmächer, Renata Shafor, Robert C. Smith, Wenche Telstad, Claudia Trenkwalder, Christian von Scheele, Arthur S. Walters, J. Catesby Ware, Marco Zucconi, Toward a better definition of the restless legs syndrome Movement Disorders. ,vol. 10, pp. 634- 642 ,(1995) , 10.1002/MDS.870100517
W Telstad, O Sorensen, S Larsen, P E Lillevold, P Stensrud, R Nyberg-Hansen, Treatment of the restless legs syndrome with carbamazepine: a double blind study. BMJ. ,vol. 288, pp. 444- 446 ,(1984) , 10.1136/BMJ.288.6415.444
C Brodeur, J Montplaisir, R Godbout, R Marinier, None, Treatment of restless legs syndrome and periodic movements during sleep with L‐dopa: A double‐blind, controlled study Neurology. ,vol. 38, pp. 1845- 1845 ,(1988) , 10.1212/WNL.38.12.1845