摘要: Publisher Summary This chapter discusses mesoderm induction. Perturbation of known signal systems may provide information on the intermediate steps in induction pathways. Regulation gene expression is a major consequence induction; studies early response genes and control tissue-specific indicate directions that will continue to yield useful results. An change cell shape adhesiveness, followed by tissue deformation. These observations suggest adhesion molecules and, possibly, cytoskeletal components during are likely be illuminating. It noted mesoderm-inducing factor (MIF) from chick embryos, named vegetalizing factor, has long been reported induce endoderm addition mesoderm. The also describes MIFs. Several members fibroblast growth (FGF) family have inducing activity, with bFGF, aFGF, kFGF having similar potency, whereas distantly related int-2 product less effective.
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