Contribution of the ankle-brachial index to improve the prediction of coronary risk: The ARTPER cohort.
作者： Rosa Forés , Maria Teresa Alzamora , Guillem Pera , José Miguel Baena-Díez , Xavier Mundet-Tuduri
DOI: 10.1371/JOURNAL.PONE.0191283
关键词:
摘要: Background The different cardiovascular risk prediction scales currently available are not sufficiently sensitive. Aim aim of the present study was to analyze contribution ankle-brachial index (ABI) added Framingham and REGICOR for reclassification after a 9-year follow up Mediterranean population with low risk. Design setting A population-based prospective cohort performed in province Barcelona, Spain. Method total 3,786 subjects >49 years were recruited from 2006–2008. Baseline ABI calculated scales. The participants followed until November 2016 by telephone review clinical history every 6 months confirm possible appearance events. Results 2,716 individuals participated study. There 126 incidental cases first coronary events (5%) during up. incidence patients <0.9 4-fold greater than that normal (17.2/1,000 persons-year versus 4.8/1,000 persons-year). Improvement predictive capacity scale observed on including model, obtaining net improvement 7% (95% confidence interval 0%-13%) REGICOR+ ABI. + obtained NRI 4% (-2%-11%). Conclusion results support addition as tool help < 0.9.
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