Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate
作者： Wen-Hsiang Chen , Lanying Du , Shivali M Chag , Cuiqing Ma , Nancy Tricoche
DOI: 10.4161/HV.27464
关键词:
摘要: … In addition, recombinant proteins RBD193 and a related construct, RBD219 (residues 318–536), expressed in the culture supernatant of mammalian cells 293T and Chinese hamster …
utsystem.edu参考文章(32)
M. Daeron, F. Kien, I. Dutry, J. S.M. Peiris, R. Bruzzone, Martial Jaume, A. Roberts, Y. W. Kam, N. Escriou, B. Nal, K. Subbarao, P. H. Li, M. S. Yip, R. Altmeyer, C. Y. Cheung, SARS CoV subunit vaccine: antibody-mediated neutralisation and enhancement. Hong Kong Medical Journal. ,vol. 18, pp. 31- 36 ,(2012)
Yuxian He, Hong Lu, Pamela Siddiqui, Yusen Zhou, Shibo Jiang, Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus Spike Protein Contains Multiple Conformation-Dependent Epitopes that Induce Highly Potent Neutralizing Antibodies The Journal of Immunology. ,vol. 174, pp. 4908- 4915 ,(2005) , 10.4049/JIMMUNOL.174.8.4908
Lanying Du, Guangyu Zhao, Yongping Lin, Hongyan Sui, Chris Chan, Selene Ma, Yuxian He, Shibo Jiang, Changyou Wu, Kwok-Yung Yuen, Dong-Yan Jin, Yusen Zhou, Bo-Jian Zheng, Intranasal Vaccination of Recombinant Adeno-Associated Virus Encoding Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-Term Protection against SARS-CoV Infection Journal of Immunology. ,vol. 180, pp. 948- 956 ,(2008) , 10.4049/JIMMUNOL.180.2.948
Fang Li, Wenhui Li, Michael Farzan, Stephen C Harrison, Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor Science. ,vol. 309, pp. 1864- 1868 ,(2005) , 10.1126/SCIENCE.1116480
Lanying Du, Virtual Ho-Chuen Leung, Xiujuan Zhang, Jie Zhou, Min Chen, Wu He, Hai-Ying Zhang, Chris C. S. Chan, Vincent Kwok-Man Poon, Guangyu Zhao, Shihui Sun, Lifeng Cai, Yusen Zhou, Bo-Jian Zheng, Shibo Jiang, A Recombinant Vaccine of H5N1 HA1 Fused with Foldon and Human IgG Fc Induced Complete Cross-Clade Protection against Divergent H5N1 Viruses PLoS ONE. ,vol. 6, pp. e16555- ,(2011) , 10.1371/JOURNAL.PONE.0016555
M. Bolles, D. Deming, K. Long, S. Agnihothram, A. Whitmore, M. Ferris, W. Funkhouser, L. Gralinski, A. Totura, M. Heise, R. S. Baric, A Double-Inactivated Severe Acute Respiratory Syndrome Coronavirus Vaccine Provides Incomplete Protection in Mice and Induces Increased Eosinophilic Proinflammatory Pulmonary Response upon Challenge Journal of Virology. ,vol. 85, pp. 12201- 12215 ,(2011) , 10.1128/JVI.06048-11
Yuxian He, Qingyu Zhu, Shuwen Liu, Yusen Zhou, Baoan Yang, Jiaming Li, Shibo Jiang, Identification of a critical neutralization determinant of severe acute respiratory syndrome (SARS)-associated coronavirus: importance for designing SARS vaccines Virology. ,vol. 334, pp. 74- 82 ,(2005) , 10.1016/J.VIROL.2005.01.034
Lanying Du, Yuxian He, Yusen Zhou, Shuwen Liu, Bo-Jian Zheng, Shibo Jiang, The spike protein of SARS-CoV — a target for vaccine and therapeutic development Nature Reviews Microbiology. ,vol. 7, pp. 226- 236 ,(2009) , 10.1038/NRMICRO2090
Ajai A. Dandekar, Stanley Perlman, Immunopathogenesis of coronavirus infections: implications for SARS Nature Reviews Immunology. ,vol. 5, pp. 917- 927 ,(2005) , 10.1038/NRI1732
Lanying Du, Guangyu Zhao, Zhihua Kou, Cuiqing Ma, Shihui Sun, Vincent KM Poon, Lu Lu, Lili Wang, Asim K Debnath, Bo-Jian Zheng, Yusen Zhou, Shibo Jiang, Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development Journal of Virology. ,vol. 87, pp. 9939- 9942 ,(2013) , 10.1128/JVI.01048-13