Mechanisms Linking Obesity to Cancer Risk
作者： Ikuyo Imayama , Caitlin Mason , Catherine Duggan
DOI: 10.1007/978-1-4419-7551-5_6
关键词:
摘要: Increased body mass and adiposity are linked to increased risk of many cancers, including postmenopausal breast, endometrial, prostate, colon cancer [1]. Obesity levels reaching epidemic proportions: the World Health Organization (WHO) estimated that in 2005, 1.6 billion individuals worldwide aged 15 years older overweight, whom 400 million obese. Projected figures for 2015 2.3 adults will be 700 obese [2]. Estimates attribute 14% US deaths [3] 25% incidence [4] excess adiposity.
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Lupien Pj, Després Jp, Lamarche B, Gagné C, Lemieux S, Moorjani S, Brun Ld, Prud'homme D, The insulin resistance-dyslipidemic syndrome: contribution of visceral obesity and therapeutic implications. International Journal of Obesity. ,vol. 19, ,(1995)
Anne McTiernan, Obesity and cancer: the risks, science, and potential management strategies. Oncology. ,vol. 19, pp. 871- 881 ,(2005)
J S Garrow, J Webster, Quetelet's index (W/H2) as a measure of fatness International Journal of Obesity. ,vol. 9, pp. 147- 153 ,(1985)
Jeffrey W. Pollard, Tumour-educated macrophages promote tumour progression and metastasis Nature Reviews Cancer. ,vol. 4, pp. 71- 78 ,(2004) , 10.1038/NRC1256
Pia K. Verkasalo, Hollie V. Thomas, Paul N. Appleby, Gwyneth K. Davey, Timothy J. Key, Circulating levels of sex hormones and their relation to risk factors for breast cancer: a cross-sectional study in 1092 pre- and postmenopausal women (United Kingdom) Cancer Causes & Control. ,vol. 12, pp. 47- 59 ,(2001) , 10.1023/A:1008929714862
J C Seidell, K van der Kooy, Techniques for the measurement of visceral fat: a practical guide International Journal of Obesity. ,vol. 17, pp. 187- 196 ,(1993)
D. J. Van Antwerp, S. J. Martin, T. Kafri, D. R. Green, I. M. Verma, Suppression of TNF-α-Induced Apoptosis by NF-κB Science. ,vol. 274, pp. 787- 789 ,(1996) , 10.1126/SCIENCE.274.5288.787
Gisela Schwab, Richard P. Nordan, Clay B. Siegall, David J. FitzGerald, Ira Pastan, Expression of the interleukin 6 receptor and interleukin 6 in prostate carcinoma cells. Cancer Research. ,vol. 50, pp. 7786- 7788 ,(1990)
Atul Purohit, Simon P Newman, Michael J Reed, The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer Breast Cancer Research. ,vol. 4, pp. 65- 69 ,(2002) , 10.1186/BCR425
Valter Donadon, Massimiliano Balbi, Pietro Casarin, Alessandro Vario, Alfredo Alberti, Association between hepatocellular carcinoma and type 2 diabetes mellitus in Italy: potential role of insulin. World Journal of Gastroenterology. ,vol. 14, pp. 5695- 5700 ,(2008) , 10.3748/WJG.14.5695