Nitrate in public water supplies and the risk of colon and rectum cancers.

作者: Anneclaire J. De Roos , Mary H. Ward , Charles F. Lynch , Kenneth P. Cantor

DOI: 10.1097/01.EDE.0000091605.01334.D3

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摘要: Background:Nitrate is a widespread contaminant of drinking water, but its potential health effects are unclear. In the body, nitrate reduced to nitrite, which can react with amines and amides by nitrosation form N-nitroso compounds, known animal carcinogens. compound formation inh

参考文章(38)
GEOFFREY R. HOWE, LARRY HARRISON, MEERA JAIN, A SHORT DIET HISTORY FOR ASSESSING DIETARY EXPOSURE TO N-NITROSAMINES IN EPIDEMIOLOGIC STUDIES American Journal of Epidemiology. ,vol. 124, pp. 595- 602 ,(1986) , 10.1093/OXFORDJOURNALS.AJE.A114432
Henrik Moller, Per Jensen, Jannik Landt, Ole Mrtllcr Jensen, Erling Pedersen, Herman Autrup, Endogenous nitrosation in relation to nitrate exposure from drinking water and diet in a Danish rural population. Cancer Research. ,vol. 49, pp. 3117- 3121 ,(1989)
S.A. Bingham, B. Pignatelli, J.R.A. Pollock, A. Ellul, C. Malaveille, G. Gross, S. Runswick, J.H. Cummings, I.K. O'Neill, Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer? Carcinogenesis. ,vol. 17, pp. 515- 523 ,(1996) , 10.1093/CARCIN/17.3.515
Gabriel Gulis, Monika Czompolyova, James R. Cerhan, An Ecologic Study of Nitrate in Municipal Drinking Water and Cancer Incidence in Trnava District, Slovakia Environmental Research. ,vol. 88, pp. 182- 187 ,(2002) , 10.1006/ENRS.2002.4331
I.R. Rowland, T. Granli, O.C. Bøckman, P.E. Key, R.C. Massey, Endogenous N-nitrosation in man assessed by measurement of apparent total N-nitroso compounds in faeces Carcinogenesis. ,vol. 12, pp. 1395- 1401 ,(1991) , 10.1093/CARCIN/12.8.1395
P.-G. Germann, H. Ernst, M. Kohler, K. Kamino, U. Mohr, Colon adenocarcinomas in European hamsters after application of N-nitroso-bis 2-oxypropyl-amine Cancer Letters. ,vol. 56, pp. 53- 58 ,(1991) , 10.1016/0304-3835(91)90193-L
Kenneth P. Cantor, Charks F. Lynch, Mariana Hildesheim, Mustafa Dosemeci, Jay Lubin, Michael Alavanja, Gunther Craun, Drinking water source and chlorination byproducts. I. Risk of bladder cancer. Epidemiology. ,vol. 9, pp. 21- 28 ,(1998) , 10.1097/00001648-199801000-00007
Peter J. Weyer, James R. Cerhan, Burton C. Kross, George R. Hallberg, Jiji Kantamneni, George Breuer, Michael P. Jones, Wei Zheng, Charles F. Lynch, Municipal Drinking Water Nitrate Level and Cancer Risk in Older Women: The Iowa Women’s Health Study Epidemiology. ,vol. 12, pp. 327- 338 ,(2001) , 10.1097/00001648-200105000-00013