作者: Alan D. Curzons , Concepción Jiménez-González , Ailsa L. Duncan , David J. C. Constable , Virginia L. Cunningham
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摘要: Background, Aim and Scope There is a clear need for simple methodology to deliver metrics that may be used determine benchmark the ‘greenness’ or relative sustainability of synthetic processes Active Pharmaceutical Ingredients (APIs). Such should facilitate more informed sustainable business choices. This capability particularly important at an early stage in R&D development activities when route are being selected detailed environmental data not available. FLASC™ (Fast Life cycle Assessment Synthetic Chemistry) web-based tool designed meet these requirements.