Neuronal subtype specification in the cerebellum and dorsal hindbrain

摘要: In the nervous system, there are hundreds to thousands of neuronal cell types that have morphologically, physiologically, and histochemically different characteristics this diversity may enable us elicit higher brain function. A better understanding molecular machinery by which neuron subtype specification occurs is thus one most important issues in science. The dorsal hindbrain, including cerebellum, a good model system study issue because variety neurons produced from region. Recently developed genetic lineage-tracing methods addition gene-transfer technologies clarified fate map hindbrain accelerated our system.