Antibiotic Stewardship for Canine and Feline Acute Urinary Tract Infection: An Observational Study in a Small Animal Hospital in Northwest Italy.

作者: Graziana Gambino , Cristina Vercelli , Giovanni Re , Mariachiara Re , Massimiliano Della Ricca

DOI: 10.3390/ANTIBIOTICS10050562

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摘要: Antimicrobial stewardship programs (ASPs) have been suggested to reduce antimicrobial resistance phenomena in veterinary medicine, as antibiotics are commonly used without microbiological confirmation. The aim of the present study is design a specific working flow for tailored treatment case canine and feline urinary tract infections (UTIs). Urine samples were collected by cystocentesis from 16 dogs 12 cats presenting acute signs UTI. therapy was decided according minimal inhibitory concentration, it possible monitor 14 11 cats. Rescue (amoxicillin clavulanic acid) included emergency cases. Escherichia coli, Proteus mirabilis, Streptococcus canis isolated dogs, Staphylococcus pseudintermedius, aureus No multidrug-resistant strains detected, but all Staphylococci methicillin resistant. Only one cat received rescue therapy, only dog recruited. Dogs treated with tetracycline (1/14), fluoroquinolones (6/14), beta-lactams gentamicin while (3/11), nitrofurans (1/11), clindamycin (6/11). success rate very high. Our findings interesting because this first ASP Italy, may be model develop ASPs other pathologies.

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