Ca2+ Antagonists as Tools in the Analysis of Excitation-Contraction Coupling in Skeletal Muscle Fibres
作者： H. Ch. Lüttgau , Th. Böhle , A. Schnier
DOI: 10.1007/978-1-4615-3362-7_11
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摘要: Organic Ca2+ antagonists are specific substances which interfere with the gating of channels. They great interest as they effective drugs in therapy different heart diseases. At present one distinguishes between three main classes antagonists: dihydropyridines (DHPs), phenylalkylamines (PAAs) and benzothiazepines (BTZs). These appear to have binding sites at channel show a reciprocal allosteric interaction among each other additional (Glossmann et al., 1985).
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