Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases

作者: Alan J Grodzinsky , N. N. Rahbari , D. Fukumura , C. Reissfelder , J. Daubriac

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摘要: The survival benefit of anti–vascular endothelial growth factor (VEGF) therapy in metastatic colorectal cancer (mCRC) patients is limited to a few months because of acquired resistance. …

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