The Conversion from Classical Studies in Fungal Pathogenesis to the Molecular Era

摘要: This chapter focuses on pioneering works that have laid the foundation for conversion from classical study of fungal pathobiology to molecular era. The most widely used and important biology-based technologies are now available in use identification pathogenic fungi also discussed. transition era necessitated development models, techniques, strategies which would facilitate definition genetic basis pathogenicity according working hypothesis Koch’s postulates formulated by Falkow. talks about versus approaches applied pathogens. Nucleic acid-based assays can be divided into two classes: PCR based non-PCR. major PCR-based diagnosis consist three different strategies, each has a standard Taq polymerase amplification template DNA as central component. discovery effective drugs vaccines knowledge biology will indeed contribute prevention therapy these infections better management patients. Education medical mycology must viewed par with other infectious diseases order realize full benefit evolution studies fungi.