Identifying the role of neutrophil-to-lymphocyte ratio and platelets-to-lymphocyte ratio as prognostic markers in patients undergoing resection of pancreatic ductal adenocarcinoma

摘要: Backgrounds/aims It is important to point out that the identification of inflammation an essential component pathogenesis and progression cancer. In this study, we analysed neutrophil-to-lymphocyte ratio (NLR) platelets-to-lymphocyte (PLR), with overall survival (OS) in patients pancreatic ductal adenocarcinoma (PDAC), who were treated a resection following or not procedure neoadjuvant chemotherapy/chemoradiation. We intended identify significance role NLR PLR, as prognostic markers undergoing surgery for PDAC. Methods There 127 enrolled study. The PLR calculated on basis pre-treatment blood cell count. An NLR>4 >120 considered be elevated measured. OS was relation values, by using both Kaplan-Meier multivariate Cox-regression methods. Results Both high associated decreased univariate analysis. analysis, NLR, but independent predictor OS. When divided into three groups (group 1: normal group 2: 3: PLR), three-years rates these 48%, 32%, 7% (p=0.001) respectively. Conclusions noted adverse factor, superior undergo PDAC