Systematic Review of Oxytocin Dosing at Caesarean Section

摘要: We undertook a systematic review to determine the optimal dose of oxytocin after elective caesarean section or in labouring women. identified seven trials. These trials raise questions about use high (10 international units; IU) moderate (5 both settings and provide evidence that lower doses are equally effective but associated with significantly fewer side-effects. For section, slow 0.3 1 IU bolus over one minute, followed by an infusion 5 10 IU.h(-1) for four hours represents evidence-based approach dosing women at low risk postpartum haemorrhage. parturient 3 oxytocin, is supported limited evidence. represent starting point control haemorrhage do not reduce need mandatory active observation clinical situation, detect situations require additional other uterotonic drugs. minimise adverse haemodynamic changes as well unpleasant side-effect nausea.