Mission Compromised? Drug-Induced Liver Injury From Prohormone Supplements Containing Anabolic–Androgenic Steroids in Two Deployed U.S. Service Members

作者: Charles D. Magee , Stephen Witte , Ryan M. Kwok , Patricia A. Deuster

DOI: 10.7205/MILMED-D-15-00502

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摘要: ABSTRACTBackground: Supplement adulteration with anabolic–androgenic steroids (AAS) has been reported and AAS-associated drug-induced liver injury is clinically variable. Objectives: We present two cases of in deployed service members, including the first report clinical hepatotoxicity desoxymethyltestosterone. highlight variable patterns AAS, raise concern inaccurate supplement labeling identify educational resources. Methods: The case presents cholestatic jaundice following 10 weeks prohormone use. Hepatobiliary imaging was unrevealing. Viral, autoimmune, metabolic etiologies were excluded. Bilirubin normalized by 8 after stopping supplement. second asymptomatic hepatocellular toxicity marked dyslipidemia identified on service-related physical 21 days Aspartate aminotransferase alanine 4 c...

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