On monotonicity of solutions of nonnegative and compartmental dynamical systems with time delays

摘要: Nonnnegative and compartmental dynamical systems with time delay play a major role in describing many processes biological medical sciences. In the specific field of pharmacokinetics, state variables represent masses or concentrations drug disposition from body. Since should monotonically decline after discontinuation administration, it is interest to determine necessary sufficient conditions under which these possess monotonic solutions. recent paper, were developed for identifying nonnegative that only admit nonoscillatory this paper we derive analogous results delays.