Polyphosphate - an ancient energy source and active metabolic regulator

摘要: There are a several molecules on Earth that effectively store energy within their covalent bonds, and one of these energy-rich is polyphosphate. In microbial cells, polyphosphate granules synthesised for both phosphate storage degraded to produce nucleotide triphosphate or phosphate. Energy released from energetic carriers used by the cell production all vital such as amino acids, nucleobases, sugars lipids. Polyphosphate chains directly regulate some processes in donors gene regulation. These two processes, metabolism regulation, orchestrated kinases. kinases (PPKs) can currently be categorized into three groups (PPK1, PPK2 PPK3) according functionality; they also divided homology (EcPPK1, PaPPK2 ScVTC). This review discusses historical information, similarities differences, biochemical characteristics, roles stress response regulation possible applications biotechnology industry enzymes. At end review, hypothesis discussed view synthetic biology states calcium-rich organelles have endosymbiotic origins ancient protocells metabolized