Changes of Serum Complement and Properdin Levels in Experimental Typhoid Fever a Longitudinal Study of the Disease including the Incubation Period and the Phase of Recovery Following Treatment with Chloramphenicol

摘要: Serum complement and properdin levels were determined throughout the incubation period entire course of experimental typhoid fever induced with one billion viable Salmonella typhosa in five six volunteers. Four patients treated chloramphenicol. The clinical disease was correlated changes serum levels, bacteremia, as well H- O-antibody titers. During period, reduction seen two cases case that failed to develop fever; titers rose three cases. early phase illness appearance first symptoms, fever, rising falling uniform all who developed disease. Clinical serological data analyzed detail. literature reviewed briefly.