Intracranial injection of LPS in rat as animal model of neuroinflammation.
作者： Ana M. Espinosa-Oliva , Rocío M. de Pablos , Antonio J. Herrera
DOI: 10.1007/978-1-62703-520-0_26
关键词:
摘要: Animal models of neuroinflammatory processes are needed to study the involvement inflammation in neurodegenerative disorders such as Parkinson's and Alzheimer's diseases. One used is based on lipopolysaccharide (LPS) brain inflammation-inducing agent. This toxin a potent inducer has different effects cells immune system, microglial cells. chapter describes protocol for model rats unilateral stereotaxic injection LPS, which mimics inflammatory milieu produced some
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