Multiple Organ Failure in Septic Shock

摘要: In the late 1960s several reports appeared describing remote organ failure (e.g., pulmonary or liver failure) as a complication of severe sepsis (Clowes et al. 1968; Skillman 1969). Stimulated by observation Tilney (1973) that sequential initially uninvolved systems may follow operations for ruptured aortic aneurysm, concept emerged injury can result in damage to distant systems. classical editorial Baue (1975) entitled“Multiple, Progressive Sequential Systems Failure: A Syndrome 1970s,”this was formulated basis a“new”clinical syndrome. Several terms were coined thereafter, such multiple (Eiseman 1977), system(s) (Border 1976), and system (Bell 1983), describe this evolving clinical syndrome otherwise unexplained progressive physiological interdependent More recently term dysfunction has been proposed more appropriate description (Bone 1992).