A biocompatible and cathepsin B sensitive nanoscale system of dendritic polyHPMA-gemcitabine prodrug enhances antitumor activity markedly.
作者： Yan Dai , Xuelei Ma , Yanhong Zhang , Kai Chen , James Z. Tang
DOI: 10.1039/C8BM00946E
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摘要: A biocompatible and cathepsin B sensitive nanoscale system of dendritic polyHPMA-gemcitabine prodrug enhances antitumor activity markedly - Biomaterials Science (RSC Publishing…
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sci-hub.se 参考文章(48)
David W. Hedley, Sylvia S. W. Ng, Ming-Sound Tsao, Sue Chow, Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells. Cancer Research. ,vol. 60, pp. 5451- 5455 ,(2000)
Rui Zhang, Kui Luo, Jiyuan Yang, Monika Sima, Yongen Sun, Margit M. Janát-Amsbury, Jindřich Kopeček, Synthesis and evaluation of a backbone biodegradable multiblock HPMA copolymer nanocarrier for the systemic delivery of paclitaxel. Journal of Controlled Release. ,vol. 166, pp. 66- 74 ,(2013) , 10.1016/J.JCONREL.2012.12.009
Anupa R. Menjoge, Rangaramanujam M. Kannan, Donald A. Tomalia, Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications Drug Discovery Today. ,vol. 15, pp. 171- 185 ,(2010) , 10.1016/J.DRUDIS.2010.01.009
S SVENSON, D TOMALIA, Dendrimers in biomedical applications--reflections on the field. Advanced Drug Delivery Reviews. ,vol. 57, pp. 2106- 2129 ,(2005) , 10.1016/J.ADDR.2005.09.018
Richard G. Cooper, James F. Holland, Oliver Glidewell, Adjuvant chemotherapy of breast cancer Cancer. ,vol. 44, pp. 793- 798 ,(1979) , 10.1002/1097-0142(197909)44:3<793::AID-CNCR2820440302>3.0.CO;2-Y
Jindřich Kopeček, Pavla Kopečková, HPMA copolymers: Origins, early developments, present, and future☆ Advanced Drug Delivery Reviews. ,vol. 62, pp. 122- 149 ,(2010) , 10.1016/J.ADDR.2009.10.004
Cong-Duan Vo, J. Rosselgong, Steven P. Armes, Norman C. Billingham, RAFT Synthesis of Branched Acrylic Copolymers Macromolecules. ,vol. 40, pp. 7119- 7125 ,(2007) , 10.1021/MA0713299
Tomáš Etrych, Lubomír Kovář, Jiří Strohalm, Petr Chytil, Blanka Říhová, Karel Ulbrich, Biodegradable star HPMA polymer-drug conjugates: Biodegradability, distribution and anti-tumor efficacy. Journal of Controlled Release. ,vol. 154, pp. 241- 248 ,(2011) , 10.1016/J.JCONREL.2011.06.015
Acharaporn Duangjai, Kui Luo, Yan Zhou, Jiyuan Yang, Jindřich Kopeček, Combination cytotoxicity of backbone degradable HPMA copolymer gemcitabine and platinum conjugates toward human ovarian carcinoma cells European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 87, pp. 187- 196 ,(2014) , 10.1016/J.EJPB.2013.11.008
Hua Wei, Ren-Xi Zhuo, Xian-Zheng Zhang, Design and development of polymeric micelles with cleavable links for intracellular drug delivery Progress in Polymer Science. ,vol. 38, pp. 503- 535 ,(2013) , 10.1016/J.PROGPOLYMSCI.2012.07.002