The effect of temperature and pH on the activity of factor VIIa: implications for the efficacy of high-dose factor VIIa in hypothermic and acidotic patients

作者: Zhi Hong Meng , Alisa S. Wolberg , Dougald M. Monroe , Maureane Hoffman

DOI: 10.1097/01.TA.0000066184.20808.A5

关键词:

摘要: Background Recombinant coagulation factor VIIa (FVIIa) is approved for treating hemophiliacs with inhibitors. High-dose FVIIa has also been used off-label to manage hemorrhage in …

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