Interferon alfa y c-ficocianina para el tratamiento de enfermedades autoinmunes, alérgicas y cáncer
作者： Rol Giselle Penton , Llanos Majel Cervantes , Nieto Gerardo Enrique Guillén , Arias Eduardo Pentón , Silva Carmen María Valenzuela
DOI:
关键词:
摘要: La presente invencion consiste en la combinacion de Interferon alfa y C- Ficocianina (IFN-α / C-Fico) obtencion una preparacion farmaceutica para el tratamiento enfermedades autoinmunes, alergicas cancer. Los efectos antinflamatorios, inmunomoduladores, antioxidantes, antivirales, antiproliferativos, antitumorales, asociados al efecto inductor celulas T reguladoras que se demuestra esta invencion, hacen racional uso IFN-α C-Fico estas enfermedades.
lens.org 参考文章(138)
Takemi Otsuki, Osamu Yamada, Haruko Sakaguchi, Akiko Tomokuni, Hideho Wada, Yoshihito Yawata, Ayako Ueki, Human myeloma cell apoptosis induced by interferon‐α British Journal of Haematology. ,vol. 103, pp. 518- 529 ,(1998) , 10.1046/J.1365-2141.1998.01000.X
M Lynch, Age-related impairment in long-term potentiation in hippocampus: a role for the cytokine, interleukin-1β? Progress in Neurobiology. ,vol. 56, pp. 571- 589 ,(1998) , 10.1016/S0301-0082(98)00054-9
Olga Savinova, Bhavesh Joshi, Rosemary Jagus, Abnormal levels and minimal activity of the dsRNA-activated protein kinase, PKR, in breast carcinoma cells. The International Journal of Biochemistry & Cell Biology. ,vol. 31, pp. 175- 189 ,(1999) , 10.1016/S1357-2725(98)00140-X
Tal Raveh, Ara G. Hovanessian, Eliane F. Meurs, Nahum Sonenberg, Adi Kimchi, Double-stranded RNA-dependent Protein Kinase Mediates c-Myc Suppression Induced by Type I Interferons Journal of Biological Chemistry. ,vol. 271, pp. 25479- 25484 ,(1996) , 10.1074/JBC.271.41.25479
R. Kumar, I. Atlas, Interferon alpha induces the expression of retinoblastoma gene product in human Burkitt lymphoma Daudi cells: role in growth regulation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 89, pp. 6599- 6603 ,(1992) , 10.1073/PNAS.89.14.6599
Amy N. Sieve, Andrew J. Steelman, Colin R. Young, Ralph Storts, Thomas H. Welsh, C. Jane R. Welsh, Mary W. Meagher, Chronic restraint stress during early Theiler's virus infection exacerbates the subsequent demyelinating disease in SJL mice. Journal of Neuroimmunology. ,vol. 155, pp. 103- 118 ,(2004) , 10.1016/J.JNEUROIM.2004.06.006
Ramandip Singh, David B Robinson, Hani S El-Gabalawy, Emerging biologic therapies in rheumatoid arthritis: cell targets and cytokines. Current Opinion in Rheumatology. ,vol. 17, pp. 274- 279 ,(2005) , 10.1097/01.BOR.0000160778.05389.DC
Yufen Qin, Dong Qing Zhang, Alexandre Prat, Sandrine Pouly, Jack Antel, Characterization of T cell lines derived from glatiramer-acetate-treated multiple sclerosis patients Journal of Neuroimmunology. ,vol. 108, pp. 201- 206 ,(2000) , 10.1016/S0165-5728(00)00263-0
B. R. Wiggs, C. Bosken, P. D. Paré, A. James, J. C. Hogg, A Model of Airway Narrowing in Asthma and in Chronic Obstructive Pulmonary Disease American Review of Respiratory Disease. ,vol. 145, pp. 1251- 1258 ,(1992) , 10.1164/AJRCCM/145.6.1251
M Y Gordon, S B Marley, J L Lewis, R J Davidson, D X Nguyen, F H Grand, T A Amos, J M Goldman, Treatment with interferon-alpha preferentially reduces the capacity for amplification of granulocyte-macrophage progenitors (CFU-GM) from patients with chronic myeloid leukemia but spares normal CFU-GM. Journal of Clinical Investigation. ,vol. 102, pp. 710- 715 ,(1998) , 10.1172/JCI3094