Fiber-optic dosimeters for radiation therapy

摘要: According to the figures provided by World Health Organization, cancer is a leading cause of death worldwide, accounting for 8.8 million deaths in 2015. Radiation therapy, which uses x-rays destroy or injure cells, has become one most important modalities treat primary advanced cancer. The newly developed microbeam radiation therapy (MRT), highly collimated, quasi-parallel arrays x-ray microbeams (typically 50 μm wide and separated 400 μm) produced synchrotron sources, represents new paradigm radiotherapy shown great promise pre-clinical studies on different animal models. Measurements absorbed dose distribution are vitally clinical acceptance MRT developing quality assurance systems MRT, hence challenging task dosimetry. On other hand, during traditional LINAC based breast brachytherapy, skin measurements treatment planning also require high spatial resolution, tissue equivalent, on-line dosimeter that both economical reliable. Such currently does not exist remains challenge development High water optical passive dosimeters have been constructed using plastic scintillators fibers. peak edge-on resolutions ranging from 500 microns dimension, with 10 micron resolution under development. fiber-optic test beams. This work demonstrates water-equivalent detection can be achieved fiber systems. Among advantages, probes passive, energy independent, hard.