DNA sequences encoding novel thrombolytic proteins
作者： Glenn R. Larsen
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摘要: Thrombolytic proteins are disclosed which have tissue plasminogen-type activity. The characterized by modification within the 94 amino acid N-terminus, and/or at Arg-275, one or more of N-linked glycosylation sites. Methods for making these as therapeutic compositions containing same.
lens.org 参考文章(3)
Diane Pennica, David Vannorman Goeddel, William Jack Kohr, Gordon Allen Vehar, Human tissue plasminogen activator ,(1983)
Jeffery Hugh Robinson, Enzyme derivatives and their use in the treatment of thrombosis ,(1983)
Herbert Louis Heyneker, Gordon Allen Vehar, Recombinant human tissue plasminogen activator muteins and genes therefor ,(1986)