Catalysis in the Service of Green Chemistry: Nobel Prize-Winning Palladium-Catalysed Cross-Couplings, Run in Water at Room Temperature: Heck, Suzuki-Miyaura and Negishi reactions carried out in the absence of organic solvents, enabled by micellar catalysis.

摘要: Abstract Palladium-catalysed cross-couplings, in particular Heck, Suzuki-Miyaura and Negishi reactions developed over three decades ago, are routinely carried out organic solvents. However, alternative media currently of considerable interest given an increasing emphasis on making processes 'greener'; for example, by minimising waste the form Water is obvious leading candidate this regard. Hence, review focuses application micellar catalysis, which a 'designer' surfactant enables these award-winning coupling to be run water at room temperature.