Pre-test probability of urinary tract infection in dogs with clinical signs of lower urinary tract disease.

作者: T.M. Sørensen , M. Holmslykke , M. Nordlund , V. Siersma , L.R. Jessen

DOI: 10.1016/J.TVJL.2019.03.003

关键词:

摘要: Abstract Clinical signs of lower urinary tract disease in dogs are characteristic but non-specific for infection. It has been hypothesized that age, sex and neuter status influences the prevalence infection (UTI), predictive value combined clinical presentation not explored dogs. The aim study was to assess predictors (sex/neuter status, dysuria/stranguria, pollakiuria, macroscopic hematuria, malodorous urine history recurrent UTI) bacterial cystitis, develop a decision rule. Data retrieved from medical records (retrospective cases) or standardized recording sheets (prospective cases). Bacterial cystitis defined as significant bacteriuria on quantitative culture with compatible disease. Dogs any breed, age were included. A total 1727 microbiology screened 424 samples included analysis. confirmed 46% cases. Four variables predicted cystitis: sex/neuter pollakiuria hematuria. score designated each variable rule constructed. This attained an AUC 0.75 had sensitivity 83% specificity 55% at its optimal cut-off (score ≥2.0). ≥3.0 positive 70%. Several factors only modest value. Other point-of-care test results should be future research optimize overall precision.

参考文章(31)
D.M. Fleming, F.F. Dobbs, A simple scoring system for evaluating symptoms, history and urine dipstick testing in the diagnosis of urinary tract infection. The Journal of the Royal College of General Practitioners. ,vol. 37, pp. 100- 104 ,(1987)
B. Mishra, S. Srivastava, K. Singh, A. Pandey, J. Agarwal, Symptom-based diagnosis of urinary tract infection in women: are we over-prescribing antibiotics? International Journal of Clinical Practice. ,vol. 66, pp. 493- 498 ,(2012) , 10.1111/J.1742-1241.2012.02906.X
J. L. Hall, M. A. Holmes, S. J. Baines, Prevalence and antimicrobial resistance of canine urinary tract pathogens Veterinary Record. ,vol. 173, pp. 549- 549 ,(2013) , 10.1136/VR.101482
Cengiz Çetin, SEZGİN ŞENTÜRK, Ali Levent Kocabiyik, Mutlu Temizel, Ebru Özel, Bacteriological Examination of Urine Samples from Dogs with Symptoms of Urinary Tract Infection Turkish Journal of Veterinary & Animal Sciences. ,vol. 27, pp. 1225- 1229 ,(2003)
D Medina-Bombardo, M Segui-Diaz, C Roca-Fusalba, J Llobera, What is the predictive value of urinary symptoms for diagnosing urinary tract infection in women Family Practice. ,vol. 20, pp. 103- 107 ,(2003) , 10.1093/FAMPRA/20.2.103
Jayawant N. Mandrekar, Receiver Operating Characteristic Curve in Diagnostic Test Assessment Journal of Thoracic Oncology. ,vol. 5, pp. 1315- 1316 ,(2010) , 10.1097/JTO.0B013E3181EC173D
Karel G.M. Moons, Douglas G. Altman, Johannes B. Reitsma, John P.A. Ioannidis, Petra Macaskill, Ewout W. Steyerberg, Andrew J. Vickers, David F. Ransohoff, Gary S. Collins, Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration. Annals of Internal Medicine. ,vol. 162, pp. 1- ,(2015) , 10.7326/M14-0698
M. Rowlands, L. Blackwood, A. Mas, P. Cripps, C. Crompton, R. Burrow, The effect of boric acid on bacterial culture of canine and feline urine. Journal of Small Animal Practice. ,vol. 52, pp. 510- 514 ,(2011) , 10.1111/J.1748-5827.2011.01102.X
A. Wayne, R. McCarthy, J. Lindenmayer, Therapeutic antibiotic use patterns in dogs: observations from a veterinary teaching hospital Journal of Small Animal Practice. ,vol. 52, pp. 310- 318 ,(2011) , 10.1111/J.1748-5827.2011.01072.X