Autoimmune Hemolytic Disease and Cryoglobulinemia Associated with Chronic Lymphocytic Leukemia* Hematologic and Metabolic Studies

摘要: Abstract 1.1. Hematologic and metabolic studies were made before, during after administration of ACTH in a case chronic lymphocytic leukemia complicated by autoimmune hemolytic disease cryoglobulinemia. 2.2. Reduction the number circulating lymphocytes, size peripheral lymph nodes rate red cell destruction was sustained for nine months following 1,250 mg. over period fifteen days. Response second series injections less dramatic but again well sustained. The possible mode action this is briefly discussed, with particular reference to effects on lymphoid tissue production or reactivity autoantibody. 3.3. During therapy expected loss nitrogen, phosphorus potassium occurred. quantitative exchange these substances, however, believed have been influenced malignant as other known hormone.