Mitochondrial metabolism in normal, myeloid, and erythroid hyperplastic rabbit bone marrow: Effect of chloramphenicol
作者： Samir Abou-Khalil , Ziad Salem , Adel A. Yunis
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摘要: Protein synthesis, respiration, and oxidative phosphorylation were studied in mitochondria isolated from normal, myeloid, erythroid hyperplastic bone marrow of rabbits. Mitochondria normal myeloid showed a similar degree 14C-leucine incorporation while threefold higher activity was demonstrated marrow. The mitochondrial-concentration-dependent all cases inhibited by low concentrations chloramphenicol (CAP). respiratory either or twice as high the but respiration unaffected CAP which totally protein synthesis.
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sci-hub.se 参考文章(16)
David R. Manyan, Una S. Smith, Adel A. Yunis, Orlando J. Martelo, Chloramphenicol and bone marrow mitochondria. Journal of Laboratory and Clinical Medicine. ,vol. 74, pp. 927- 940 ,(1969) , 10.5555/URI:PII:0022214369900754
DB ROODYN, PJ REIS, TS WORK, Protein synthesis in mitochondria. Requirements for the incorporation of radioactive amino acids into mitochondrial protein Biochemical Journal. ,vol. 80, pp. 9- 21 ,(1961) , 10.1042/BJ0800009
M. S. Jones, O. T. G. Jones, The structural organization of haem synthesis in rat liver mitochondria. Biochemical Journal. ,vol. 113, pp. 507- 514 ,(1969) , 10.1042/BJ1130507
Allan G. Gornall, Charles J. Bardawill, Maxima M. David, Determination of serum proteins by means of the biuret reaction. Journal of Biological Chemistry. ,vol. 177, pp. 751- 766 ,(1949) , 10.1016/S0021-9258(18)57021-6
G. E. W. Wolstenholme, Cecilia M. O'Connor, Ciba Foundation Symposium on the Regulation of Cell Metabolism ,(2011)
R.J. Rascati, P. Parsons, Biosynthesis of cytochrome c oxidase by isolated rat liver mitochondria. Journal of Biological Chemistry. ,vol. 254, pp. 1594- 1599 ,(1979) , 10.1016/S0021-9258(17)37813-4
A.M. Kroon, Protein synthesis in mitochondria Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects. ,vol. 91, pp. 145- 154 ,(1964) , 10.1016/0926-6550(64)90178-1
Alexander Tzagoloff, Pauline Meagher, Assembly of the Mitochondrial Membrane System VI. MITOCHONDRIAL SYNTHESIS OF SUBUNIT PROTEINS OF THE RUTAMYCIN-SENSITIVE ADENOSINE TRIPHOSPHATASE Journal of Biological Chemistry. ,vol. 247, pp. 594- 603 ,(1972) , 10.1016/S0021-9258(19)45744-X
M Ashwell, T S Work, The Biogenesis of Mitochondria Annual Review of Biochemistry. ,vol. 39, pp. 251- 290 ,(1970) , 10.1146/ANNUREV.BI.39.070170.001343
Eugene C. Weinbach, A procedure for isolating stable mitochondria from rat liver and kidney. Analytical Biochemistry. ,vol. 2, pp. 335- 343 ,(1961) , 10.1016/0003-2697(61)90006-9